A vanishing complication of haemodialysis: Dialysis disequilibrium syndrome

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Dialysis Disequilibrium Syndrome: A Neurological Manifestation of Haemodialysis

Renal insufficiency has many protean effects on the central nervous system. Early symptoms such as fatigue, clumsiness, and impaired concentration may progress to hallucinations, agitation, disorientation and coma if the renal insufficiency is untreated. The pathophysiology of these changes, due to uraemic encephalopathy are thought to be mediated by impaired neurotransmission (Burn & Bates, 19...

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Dialysis disequilibrium syndrome: A preventable fatal acute complication.

Dialysis disequilibrium syndrome (DDS) is a neurological disorder with varying severity that is postulated to be associated with cerebral oedema. We described a case of DDS resulting in irreversible brain injury and death following acute haemodialysis. A 13-year-old male with no past medical history and weighing 30kg, presented to hospital with severe urosepsis complicated by acute kidney injur...

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Dialysis Disequilibrium Syndrome

A aggressive dialysis in a grossly azotemic patient, especially one with severe metabolic acidosis, can lead to dialysis disequilibrium syndrome (DDS). Mild forms present as nausea, vomiting, restlessness, and headache. Severe manifestations include seizures, obtundation, coma, and even death. This clinical picture is caused by cerebral edema induced by one or more of the following mechanisms:

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Sepsis and Dialysis Disequilibrium Syndrome

Dialysis disequilibrium syndrome (DDS) is a central nervous system disorder, usually occurs in patients during hemodialysis (HD) or within 24 hours of HD. DDS was first described by Kennedy et al. in 1962. 11 If a critically ill patient on HD develops severe sepsis and septic shock with multiple organ failure (MOF), the adverse effect of HD on the brain is likely to be amplified, which may pred...

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Twenty eight patients who had received haemodialysis for more than 10 years were reviewed to establish the incidence of joint problems. Only six patients had no joint symptoms, one had avascular necrosis, one had had recent septic arthritis, and four had hyperparathyroidism. The remaining 16 patients had no evidence of hyperparathyroidism yet had an arthropathy causing pain and stiffness in man...

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ژورنال

عنوان ژورنال: Journal of the Intensive Care Society

سال: 2018

ISSN: 1751-1437

DOI: 10.1177/1751143718798585